human GPR65 receptor, also known as TDAG8 for T cell death-associated gene 8, is validated for cAMP and IPOne assays; even though the main coupling is Gs, IPone assays can be employed for confirmations

Target Information

Family :
pH sensing
Receptor :

GPR65

Species :
Homo sapiens
Accession number :
NP_003599.2

Assay Information

Cat. Number :
FAST-0927I
Method :
HTRF
Assay Type :
IPOne
Source :
1321N1

Testing Information

Mode:
agonist
Reference agonist:
pH (H+)
EC50:
pH 7.1*
no reference antagonist available
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot