As part of the original Euroscreen S.A. spin-off founded in 1994, we’ve benefited from a buoyant research and development environment focused on GPCR science. This expertise was nurtured over the past two decades by taking part in many GPCR deorphanization programs, developing hundreds of cell lines and screening assays, and assisting our customers in their drug discovery efforts.
Our ever-growing catalogue of recombinant GPCR assays has more than 530 targets represented by over 1,000 functional and radioligand binding assays that can be used for high throughput screening, molecular pharmacology and profiling with various readouts. We’ve also developed a unique GPCR deorphanization platform which has been used for the successful identification of 17 new receptor-ligand pairs.
Our GPCR Screening Assay Catalogue give you access to more than 530 GPCR, represented by over 1,000 binding and functional assays. Readouts include Aequorin (calcium), cAMP, IPOne, GTPγS, ERK1/2, internalization, radioligand binding and TagLite® binding.
We offer to develop fully-customized recombinant cell lines expressing your target of interest and characterized by an assay of choice.
We give you access to our unique GPCR deorphanization platform and one of the best scientific track-record with 17 successful deorphanization programs in our 30 years history.
We are offering ready-to-use profiling packages (target family-based, therapeutic area-based…) but you can also pick your targets of choice from our catalogue to set-up your personalized panel.
