human Melatonin MT2 receptor is also validated for Aequorin (calcium) and radioligand binding competition assays

Target Information

Family :
Melatonin
Receptor :

MT2

Species :
Homo sapiens
Accession number :
NP_005950.1

Assay Information

Cat. Number :
FAST-0241G
Method :
SPA
Assay Type :
GTPγS
Source :
CHO-K1

Testing Information

Mode:
agonist
Reference agonist:
2-iodo-melatonin
EC50:
0.24nM*
#ALT#
Mode:
antagonist
Reference antagonist:
Luzindole
IC50:
309nM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot