Syrian hamster (golden hamster) CCR5 receptor is validated for Aequorin (calcium) assays

Target Information

Family :
Chemokine
Receptor :

CCR5

Species :
Mesocricetus auratus
Accession number :
XP_005082336.1

Assay Information

Cat. Number :
FAST-0714A
Method :
luminescence
Assay Type :
aequorin (calcium)
Source :
CHO-K1-mt aequorin-Gα16

Testing Information

Mode:
agonist
Reference agonist:
CCL5 (RANTES)
EC50:
1.33nM*
#ALT#
Mode:
antagonist
Reference antagonist:
Maraviroc
IC50:
12.1µM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot