Human CGRP (Calcitonin receptor-like/RAMP1) receptor is also available for cAMP and radioligand binding assays

Target Information

Family :
Calcitonin
Receptor :

CGRP (CRLR/RAMP1)

Species :
Homo sapiens
Accession number :
NP_005786.1 (CRLR); NP_005846.1 (RAMP1)

Assay Information

Cat. Number :
FAST-025A
Method :
luminescence
Assay Type :
aequorin (calcium)
Source :
CHO-K1-mt aequorin-Gqs

Testing Information

Mode:
agonist
Reference agonist:
α-CGRP
EC50:
3.25nM*
#ALT#

Mode:
antagonist
Reference antagonist:
SB 268262
IC50:
192nM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot