mouse CGRP (mouse Calcitonin receptor-like and mouse RAMP1) receptor is validated for cAMP HTRF assays

Target Information

Family :
Calcitonin
Receptor :

CGRP (CRLR/RAMP1)

Species :
Mus musculus
Accession number :
NP_061252.2 (CRLR); NP_058590.1 (RAMP1)

Assay Information

Cat. Number :
FAST-054C
Method :
HTRF
Assay Type :
cAMP – Gs mode
Source :
CHO-K1

Testing Information

Mode:
agonist
Reference agonist:
α-CGRP
EC50:
1.65pM*
#ALT#

Mode:
antagonist
Reference antagonist:
MK 0974
IC50:
17.2µM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot