FAST-0603A
Chemokine CCR5 Aequorin
mouse CCR5 is also available for cAMP HTRF and radioligand binding competition assays.
Target Information
- Family :
- Chemokine
- Receptor :
-
CCR5
- Species :
- Mus musculus
- Accession number :
- NP_034047.2
Assay Information
- Cat. Number :
- FAST-0603A
- Method :
- luminescence
- Assay Type :
- aequorin (calcium)
- Source :
- CHO-K1-mt aequorin-Gα16
- Mode:
- Agonist
- Reference agonist:
- CCL4 (MIP-1β)
- EC50:
- 0.44nM*
Testing Information
- Mode:
- agonist
- Reference agonist:
- mouse CCL5 (mouse RANTES)
- EC50:
- 0.75nM*
- Mode:
- antagonist
- Reference antagonist:
- Maraviroc
- IC50:
- 7.8µM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot