FAST-0711C
Chemokine CCR5 cAMP
monkey CCR5 receptor is also validated Aequorin (calcium) and radioligand binding competition assays
Target Information
- Family :
- Chemokine
- Receptor :
-
CCR5
- Species :
- Macaca mulatta, Macaca fascicularis
- Accession number :
- AAB62554.1
Assay Information
- Cat. Number :
- FAST-0711C
- Method :
- HTRF
- Assay Type :
- cAMP – Gi mode
- Source :
- CHO-K1
Testing Information
- Mode:
- agonist
- Reference agonist:
- CCL4 (MIP-1β)
- EC50:
- 0.27nM*
- Mode:
- antagonist
- Reference antagonist:
- Maraviroc
- IC50:
- 11.9nM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot