human CX3CR1 receptor is also validated for Aequorin (calcium), cAMP, ERK1/2 and radioligand binding competition assays

Target Information

Family :
Chemokine
Receptor :

CX3CR1

Species :
Homo sapiens
Accession number :
NP_001328.1

Assay Information

Cat. Number :
FAST-070G
Method :
SPA
Assay Type :
GTPγS
Source :
CHO-K1

Testing Information

Mode:
agonist
Reference agonist:
CX3CL1 (Fractalkine)
EC50:
0.58nM*
#ALT#

Mode:
antagonist
Reference antagonist:
vMIP-II
IC50:
188nM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot