FAST-077A
Chemokine CXCR4 Aequorin
human CXCR4 receptor is also validated for cAMP, GTPγS and radioligand binding competition assays
Target Information
- Family :
- Chemokine
- Receptor :
-
CXCR4
- Species :
- Homo sapiens
- Accession number :
- NP_003458.1
Assay Information
- Cat. Number :
- FAST-077A
- Method :
- luminescence
- Assay Type :
- aequorin (calcium)
- Source :
- CHO-K1-mt aequorin-Gα16
Testing Information
- Mode:
- agonist
- Reference agonist:
- CXCL12 (SDF-1α)
- EC50:
- 2.24nM*
- Mode:
- antagonist
- Reference antagonist:
- AMD 3100
- IC50:
- 4.13nM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot