FAST-077C
Chemokine CXCR4 cAMP
human CXCR4 receptor is also validated for Aequorin (calcium), GTPγS and radioligand binding competition assays
Target Information
- Family :
- Chemokine
- Receptor :
-
CXCR4
- Species :
- Homo sapiens
- Accession number :
- NP_003458.1
Assay Information
- Cat. Number :
- FAST-077C
- Method :
- HTRF
- Assay Type :
- cAMP – Gi mode
- Source :
- CHO-K1
Testing Information
- Mode:
- agonist
- Reference agonist:
- CXCL12 (SDF-1α)
- EC50:
- 1.08nM*
- Mode:
- antagonist
- Reference antagonist:
- AMD 3100
- IC50:
- 961nM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot