human CRF1 receptor is also validated for Aequorin (calcium), GTPγS and radioligand binding competition assays

Target Information

Family :
Corticotropin-releasing factor
Receptor :

CRF1

Species :
Homo sapiens
Accession number :
NP_004373.2

Assay Information

Cat. Number :
FAST-095C
Method :
HTRF
Assay Type :
cAMP – Gs mode
Source :

Testing Information

Mode:
agonist
Reference agonist:
Urocortin
EC50:
5.38nM*
#ALT#
Mode:
Antagonist
Reference antagonist:
CRF (9-41)
IC50:
174nM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot