FAST-0120C
GABA GABA B1a/B2 cAMP
human GABA B1a/B2 heteromer is validated for Aequorin (calcium), GTPγS and radioligand binding competition assays
Target Information
- Family :
- GABA B
- Target :
- GABA B1a/B2
- Species :
- Homo sapiens
- Accession number :
- CAA09939.1 / CAA09942.1
Assay Information
- Cat. Number :
- FAST-0120C
- Method :
- HTRF
- Assay Type :
- cAMP – Gi mode
- Source :
- CHO-K1
Testing Information
- Mode:
- agonist
- Reference agonist:
- GABA
- EC50:
- 569nM*
- Mode:
- PAM
- Reference PAM:
- CGP 7930
- EC50:
- 4.3µM*
- Mode:
- antagonist
- Reference antagonist:
- CGP 54626
- IC50:
- 2.92nM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot