human GABA B1a/B2  heteromer is also validated for Aequorin (calcium), cAMP and radioligand binding competition assays

Target Information

Family :
GABA B
Target :
GABA B1a/B2
Species :
Homo sapiens
Accession number :
CAA09939.1 / CAA09942.1

Assay Information

Cat. Number :
FAST-0120G
Method :
SPA
Assay Type :
GTPγS
Source :
CHO-K1
Mode:
agonist
Reference agonist:
GABA
Ec50:
11.2µM*
#ALT#

Testing Information

Mode:
agonist
Reference agonist:
SKF 97541
EC50:
6.89µM*
#ALT#

Mode:
antagonist
Reference antagonist:
CGP 54626
IC50:
21.8nM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot