mouse GLP-1 receptor is also validated for radioligand binding competition and internalisation assays

Target Information

Family :
Glucagon
Receptor :

GLP-1

Species :
Mus musculus
Accession number :
NP_067307.2

Assay Information

Cat. Number :
FAST-0147C
Method :
HTRF
Assay Type :
cAMP – Gs mode

Testing Information

Source:
β-TC-6
Mode:
agonist
Reference agonist:
GLP-1 (7-36)
EC50:
0.11nM*
#ALT#
Source:
HEK293
Mode:
agonist
Reference agonist:
Exendin-4
EC50:
0.70pM*
#ALT#

Source:
β-TC-6
Mode:
antagonist
Reference antagonist:
Exendin-3 (9-39)
IC50:
3.13nM*
#ALT#
Source:
HEK293
Mode:
antagonist
Reference antagonist:
Exendin-3 (9-39)
IC50:
34.3nM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot