human Melatonin MT1 receptor is also validated for GTPγS and radioligand binding competition assays

Target Information

Family :
Melatonin
Receptor :

MT1

Species :
Homo sapiens
Accession number :
NP_005949.1

Assay Information

Cat. Number :
FAST-0240A
Method :
luminescence
Assay Type :
aequorin (calcium)
Source :
CHO-K1-mt aequorin-Gα16

Testing Information

Mode:
agonist
Reference agonist:
2-iodo-melatonin
EC50:
6.63nM*
#ALT#

Mode:
antagonist
Reference antagonist:
Luzindole
IC50:
1.42µM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot