ES-212I
Muscarinic M3 IPOne
human Muscarinic M3 receptor is also validated for Aequorin (calcium) and radioligand binding competition assays
Target Information
- Family :
- Muscarinic
- Receptor :
-
M3
- Species :
- Homo sapiens
- Accession number :
- NP_000731.1
Assay Information
- Cat. Number :
- Es-212I
- Method :
- HTRF
- Assay Type :
- IPOne
- Source :
- CHO-K1
Testing Information
- Mode:
- agonist
- Reference agonist:
- Acetylcholine
- EC50:
- 174nM*
- Mode:
- antagonist
- Reference antagonist:
- 4-DAMP
- IC50:
- 2.51nM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot