human Muscarinic M4 receptor is also validated for GTPγS and radioligand binding competition assays

Target Information

Family :
Muscarinic
Receptor :

M4

Species :
Homo sapiens
Accession number :
NP_000732.1

Assay Information

Cat. Number :
ES-213A
Method :
luminescence
Assay Type :
aequorin (calcium)
Source :
CHO-K1-mt aequorin-Gα16

Testing Information

Mode:
agonist
Reference agonist:
Acetylcholine
EC50:
63.1nM*
#ALT#

Mode:
antagonist
Reference antagonist:
N-Me-Scopolamine
IC50:
0.068nM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot