ES-213G
Muscarinic M4 GTPγS
human Muscarinic M4 receptor is also validated for Aequorin (calcium) and radioligand binding competition assays
Target Information
- Family :
- Muscarinic
- Receptor :
-
M4
- Species :
- Homo sapiens
- Accession number :
- NP_000732.1
Assay Information
- Cat. Number :
- ES-213G
- Method :
- SPA
- Assay Type :
- GTPγS
- Source :
- CHO-K1
Testing Information
- Mode:
- agonist
- Reference agonist:
- Oxotremorine
- EC50:
- 379nM*
- Mode:
- antagonist
- Reference antagonist:
- 4-DAMP
- IC50:
- 8.56nM*
- Mode:
- PAM
- Reference PAM:
- LY 203398
- EC50:
- 179nM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot