human Muscarinic M5 is also validated for Aequorin (calcium) and radioligand binding competition assays

Target Information

Family :
Muscarinic
Receptor :

M5

Species :
Homo sapiens
Accession number :
NP_036257.1

Assay Information

Cat. Number :
FAST-0264I
Method :
HTRF
Assay Type :
IPOne
Source :
CHO-K1

Testing Information

Mode:
agonist
Reference agonist:
Acetylcholine
EC50:
181nM*
#ALT#

Mode:
antagonist
Reference antagonist:
4-DAMP
IC50:
5.38nM*
#ALT#
Mode:
PAM
Reference PAM:
VU238429
EC50:
5.66µM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot