FAST-0381B
Opioid OP3 (mu) Binding
human mu Opioid receptor, also known as OP3, is also validated for Aequorin (calcium), cAMP, GTPγS, ERK1/2 and radioligand binding competition assays
Target Information
- Family :
- Opioid
- Receptor :
-
OP3 (μ)
- Species :
- Homo sapiens
- Accession number :
- NP_000905.3
Assay Information
- Cat. Number :
- FAST-0381B
- Method :
- radiometric
- Assay Type :
- filtration binding
- Source :
- CHO-K1
Testing Information
- Mode:
- competition
- Tracer (agonist):
- [3H] DAMGO
- Tracer concentration:
- 0.75nM
- Reference competitor:
- DAMGO
- IC50:
- 5.52nM*
- Mode:
- competition
- Tracer (antagonist):
- [3H] Naloxone
- Tracer concentration:
- 1nM
- Reference competitor:
- DAMGO
- IC50:
- 49.2nM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot