FAST-0381C
Opioid OP3 (mu) cAMP
human mu Opioid receptor, also known as OP3, is also validated for Aequorin (calcium), cAMP, GTPγS, ERK1/2 and radioligand binding competition assays
Target Information
- Family :
- Opioid
- Receptor :
-
OP3 (μ)
- Species :
- Homo sapiens
- Accession number :
- NP_000905.3
Assay Information
- Cat. Number :
- FAST-0381C
- Method :
- HTRF
- Assay Type :
- cAMP – Gi mode
- Source :
- CHO-K1
Testing Information
- Mode:
- agonist
- Reference agonist:
- DAMGO
- EC50:
- 1.99nM*
- Mode:
- antagonist
- Reference antagonist:
- CTOP
- IC50:
- 36.8nM*
- Mode:
- PAM
- Reference PAM:
- BMS 986122
- EC50:
- 6.98µM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot