FAST-0927C
pH sensing GPR65 cAMP
human GPR65 receptor, also known as TDAG8 for T cell death-associated gene 8, is validated for cAMP and IPOne assays; even though the main coupling is Gs, IPone assays can be employed for confirmations
Target Information
- Family :
- pH sensing
- Receptor :
-
GPR65
- Species :
- Homo sapiens
- Accession number :
- NP_003599.2
Assay Information
- Cat. Number :
- FAST-0927C
- Method :
- HTRF
- Assay Type :
- cAMP – Gs mode
- Source :
- 1321N1
Testing Information
- Mode:
- agonist
- Reference agonist:
- pH (H+)
- EC50:
- pH 7.1*
- no reference antagonist available
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- Mode:
- agonist
- Reference agonist:
- BTB09089
- EC50:
- 1.99µM*
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- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot