human Sphingosine S1P1 receptor, also known as EDG1, is also validated for Aequorin (calcium) assays

Target Information

Family :
Sphingosine
Receptor :

S1P1 (EDG1)

Species :
Homo sapiens
Accession number :
NP_001391.2

Assay Information

Cat. Number :
FAST-0197C
Method :
HTRF
Assay Type :
cAMP – Gi mode
Source :
CHO-K1

Testing Information

Mode:
agonist
Reference agonist:
Sphingosine 1-phosphate (S1P)
EC50:
4.02nM*
#ALT#
Mode:
antagonist
Reference antagonist:
W146
IC50:
112nM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot