FAST-0197G
Lysophospholipid S1P1 (EDG1) GTPγS
human Sphingosine S1P1 receptor, also known as EDG1, is also validated for cAMP and aequorin (calcium) assays
Target Information
- Family :
- Sphingosine
- Receptor :
-
S1P1 (EDG1)
- Species :
- Homo sapiens
- Accession number :
- NP_001391.2
Assay Information
- Cat. Number :
- FAST-0197G
- Method :
- SPA
- Assay Type :
- GTPγS
- Source :
- CHO-K1-mt aequorin-Gqi5
Testing Information
- Mode:
- agonist
- Reference agonist:
- Sphingosine 1-phosphate (S1P)
- EC50:
- 20.1nM*
- Mode:
- agonist
- Reference agonist:
- FTY720-P
- EC50:
- 1.29nM*
- Mode:
- antagonist
- Reference antagonist:
- W 146
- IC50:
- 537nM*
- Standard TAT :
- 15 Business Days
- Fast TAT :
- 5 Business Days
- * Value is subjected to variation from lot to lot