human Sphingosine S1P4 receptor, also known as EDG6, is also validated for internalisation assays

Target Information

Family :
Sphingosine
Receptor :

S1P4 (EDG6)

Species :
Homo sapiens
Accession number :
NP_003766.1

Assay Information

Cat. Number :
FAST-0200A
Method :
luminescence
Assay Type :
aequorin (calcium)
Source :
CHO-K1-mt aequorin-Gqi5

Testing Information

Mode:
agonist
Reference agonist:
Sphingosine 1-phosphate (S1P)
EC50:
76.6nM*
#ALT#

Mode:
antagonist
Reference antagonist:
CYM 50358
IC50:
21.9nM*
#ALT#
Standard TAT :
15 Business Days
Fast TAT :
5 Business Days
* Value is subjected to variation from lot to lot