EuroscreenFast issues a new catalogue update adding 50 brand new assays
Since the latest catalogue update in 2017, we have developed 50 new assays, including 27 new cell lines (marked with an *).
June 1, 2018
Family | Target | Species | Coupling | Readout | Catalogue Number |
Adenosine | A1 | MM | Gi/o | GTPgS | FAST-031G |
A2A | MM | Gs | cAMP | FAST-032C | |
A2B* | MM | Gs | cAMP | FAST-033C | |
MM | Gs | Binding | FAST-033B | ||
A3 | MM | Gi/o | cAMP | FAST-034C | |
MM | Gi/o | GTPgS | FAST-034G | ||
Adrenergic | a2B | CF | Gi/o | Aequorin | FAST-013A |
Calcitonin | AMY1 (CTR/RAMP1)* | HS | Gs | cAMP | FAST-035C |
AMY2 (CTR/RAMP2)* | HS | Gs | cAMP | FAST-036C | |
CTR* | HS | Gs | cAMP | FAST-030C | |
Chemokine | CCR5* | OC | Gi/o | Aequorin | FAST-0713A |
CCR8 | HS | Gi/o | cAMP | FAST-065C | |
MM | Gi/o | cAMP | FAST-0606C | ||
Dopamine | D2S | HS | Gi/o | GTPgS | FAST-0102G |
D4.4 | RN | Gi/o | GTPgS | FAST-0103G | |
Formylpeptide | FPR1 (fMLP) | HS | Gi/o | cAMP | FAST-0342C |
Ghrelin | GHS-R | HS | Gq/11 | IPOne | FAST-0135I |
Orphan | GPR52* | RN | Gs | cAMP | FAST-0961C |
GPR142* | MM | Gq/11 | IPOne | FAST-0898I | |
RN | Gq/11 | IPOne | FAST-0899I | ||
Histamine | H4* | MM | Gi/o | GTPgS | FAST-0169G |
Hydroxycarboxylic acid | GPR109b (HM74/HCA3) | HS | Gi/o | GTPgS | FAST-0351G |
HS | Gi/o | ERK1/2 | FAST-0351E | ||
GPR81 (HCA1)* | RN | Gi/o | cAMP | FAST-0354C | |
Melanocortin | MC5 | MM | Gs | Binding | FAST-0236B |
MC5* | RN | Gs | cAMP | FAST-0237C | |
CF | Gs | cAMP | FAST-0238C | ||
Muscarinic | M2 | RN | Gi/o | cAMP | FAST-0263C |
Neurokinin | NK1* | RH | Gq/11 | Aequorin | FAST-0634A |
NK2* | RH | Gq/11 | Aequorin | FAST-0635A | |
NK3 | RH | Gq/11 | Binding | FAST-0275B | |
Neuropeptide | NPY2 | RN | Gq/11, Gi/o | Binding | FAST-0324B |
MF | Gq/11, Gi/o | Binding | FAST-0325B | ||
NPY4 | HS | Gq/11, Gi/o | Binding | FAST-0323B | |
NPY5 | HS | Gi/o | Binding | FAST-0322B | |
Neurotensin | NTS1 | HS | Gq/11 | IPOne | FAST-0330I |
Orexin | OX1* | MM | Gq/11 | Aequorin | FAST-0394A |
OX2* | MM | Gq/11 | Aequorin | FAST-0395A | |
Prokineticin | PKR2 | HS | Gq/11, Gs | cAMP | FAST-0401C |
PKR2 | HS | Gq/11, Gs | IPOne | FAST-0401I | |
Relaxin | RXFP1* | MM | Gs | cAMP | FAST-0464C |
RN | Gs | cAMP | FAST-0465C | ||
CF | Gs | cAMP | FAST-0466C | ||
OC | Gs | cAMP | FAST-0467C | ||
SS | Gs | cAMP | FAST-0468C | ||
Serotonin | 5-HT7a* | RN | Gs | cAMP | FAST-0499C |
Vasopressin | V1a* | MM | Gq/11 | Aequorin | FAST-0546A |
OC | Gq/11 | Aequorin | FAST-0547A | ||
OT (oxytocin)* | MM | Gq/11 | Aequorin | FAST-0548A | |
OC | Gq/11 | Aequorin | FAST-0549A |